Recent remmina versions can set RDP remote windows desktop scaling factor. From the global preferences menu -> RDP. But you need an updated remmina version and an OS (windows 8.1 or higher) that supports scaling factor. Upgrade remmina following instructions on the main website We provide a PPA for ubuntu 16.04.If you already enabled local scaling on your local PC, and usually this is the case when using a 4K monitor, you should also play with the remmina scaler function to neutralize the Xorg/Unity scaling, because remmina can't currently do to it.