I too am having the same issues with driver updates after 2.81 release. Followed steps as outlined on Line 6 website. I also troubleshooted process with the steps similar to what Has been posted by Chrisj1990. What is odd is that the USB driver is recognized within windows10 Device Manager as Line 6 - Helix Floor and also within Windows Control Panel items as Heilx Control Panel yet both HX Editor (2.9) and Editor (1.19) but yet Line 6 software just wont' acknowledge connection within the software.