The primary difference between Windows 10 Home and Pro lies in the features they offer. Windows 10 Pro has all the features of Windows 10 Home, plus additional features such as Domain Join, Group Policy Management, BitLocker, Enterprise Mode Internet Explorer (EMIE), Assigned Access 8.1, Remote Desktop, Client Hyper-V, and Direct Access. Additionally, Windows 10 Pro supports Windows Information Protection (WIP) and Windows Sandbox, while these features are not available in the Home edition.