The IHEC has the authority to approve, require modifications to secure approval, and disapprove all research activities overseen and conducted by the organizations. The IHEC has the authority to suspend, place restrictions, or terminate approval of research activities that fall within its jurisdiction that are not being conducted in accordance with IHEC requirements or that have been associated with serious harm to subjects. The IHEC has the authority to observe or have a third party observe the consent process and/or the research if the IHEC determines it to be indicated.