What Happens After Spider Man No Way Home

we are facing since few weeks the problem that Office Apps (Word, Excel, Powerpoint, not Outlook) are constantly crashing for a few users when they try to open a document from Sharepoint Online, similar if it from Teams, Sharepoint or a mapped network drive to a sharepoint library. The eventlog is showing the known error with the mso20win32client.dll file, but all suggestions to fix this problem didn't help unfortinately. Curiously the Office programs are working when the same document ist copied locally on the C: drive^^