I just thought I would throw in an alternative answer. I just updated Origin to the latest version, having run it for the first time since I upgraded to Windows 8.1. I was encountering Error 262145:5 on all my downloads (initial downloads, so I had no existing folders on my hard drives to delete, indicating that the other answers to this question did not apply). When I exited, Windows popped up that familiar "Did this program run correctly?" dialog, and I ran through it.