Although the user may be working on a local copy of document but OneDrive might be trying to sync the files/changes in which case it will put a lock on the file for the duration of the sync. (hence the delay - not responding)
Although the user may be working on a local copy of document but OneDrive might be trying to sync the files/changes in which case it will put a lock on the file for the duration of the sync. (hence the delay - not responding)