Detection of Alzheimer's disease has traditionally involved screening individuals for symptoms of cognitive impairment, such as forgetfulness, followed by invasive and expensive tests, such as PET scans and cerebrospinal fluid tests, to confirm a diagnosis. Interventions to stall or potentially mitigate Alzheimer's disease, including behavioral changes (such as exercising more) or use of emerging Alzheimer's disease therapies, may be most effective when initiated in the early stages of Alzheimer's disease.