Jupyter Notebook is a powerful tool for data scientists and software engineers. However, running out of memory can be a frustrating experience. In this article, we discussed several ways to clear the memory of a running Jupyter Notebook without restarting it. These methods include deleting unused variables, clearing output, using %reset, using gc.collect(), and using a context manager. By using these methods, you can free up memory and continue working with your notebook without losing any unsaved work.