Her first call-up for Brazil came in 2018 following a successful first season with FC Girondins de Bordeaux in France, which netted a two-year contract extension. Though Brazil eventually lost to France in a thrilling round of 16 tie at the 2019 World Cup, Sousa flourished after being tabbed a starter prior to the tournament, becoming the youngest player in the lineup. After a two-year stint at Inter Milan in Italy from 2020-22, she signed with Real Madrid in Spain ahead of the 2022-23 season where she became a regular feature for the European giants, making 26 appearances.