Losing the connection to FirefoxPortable\Data\plugins\ shouldn't be a major issue as you may move the plugins located here to FirefoxPortable\App\firefox\plugins\, where Firefox will find them as well.
Losing the connection to FirefoxPortable\Data\plugins\ shouldn't be a major issue as you may move the plugins located here to FirefoxPortable\App\firefox\plugins\, where Firefox will find them as well.