First, you can play one or more cards of any suit (there are seven suits in The Deadlies!). You can also play any number of cards with the same number. Lastly, you may play a straight of any length, even if it is made up of only two cards. In all cases, whatever the topmost card was, its effect will be resolved immediately. These range from forcing others to reveal cards in their hand, drawing additional cards or even trading your entire hand with another player!