Culturally, the song taps into themes of gender identity and societal norms, albeit in a humorous and exaggerated manner. Los Morancos are known for their ability to blend humor with social commentary, and "Ni Juana Ni Juan" is no exception. The song encourages listeners to question their assumptions and find humor in the unexpected, all while enjoying a catchy and entertaining tune. The playful narrative and comedic delivery make this song a memorable and enjoyable experience, showcasing Los Morancos' unique style and talent for satire.